Quinine Hydrochloride Dihydrate
CAS 6119-47-7
Purity: 99%
Related products: Quinine monohydrochloride dihydrate, Quinine (hydrochloride dihydrate)
Common Name | Quinine Hydrochloride Dihydrate | ||
CAS Number | 6119-47-7 | Molecular Weight | 396.908 |
Density | N/A | Boiling Point | 633ºC at 760 mmHg |
Molecular Formula | C20H29ClN2O4 | Melting Point | 115-116 °C (dec.)(lit.) |
Brand | SHXLCHEM | Flash Point | 122 °C |
Items | Specifications | Results |
Appearance | White to off-white Powder | Complies |
Solubility | Soluble in water, freely soluble in ethanol (96%). | Complies |
Identification | ||
A) TLC | The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution. | Complies |
B) Bromine and ammonia | A green colour develops when treated with bromine water and dilute ammonia | Complies |
C) IR Spectrum | When examined in ultraviolet light at 366 nm,an intense blue fluorescence appears which disappears almost completely on the addition of 1 ml of HCL | Complies |
D) Characteristic of chlorides | It gives the reactions of chlorides | Complies |
E) Test for pH | Should comply | Complies |
Appearance of solution | Solution S is clear and not more intensely coloured than reference solution GY6 | Complies |
pH | 6.0~6.8 | 6.40 |
Specific optical rotation | -240° ~ -226° | Complies |
Titration with AgNO3 | 95.0 - 105.0 % | Complies |
Other cinchona alkaloids
Impurity C Any impurity eluted before quinine Any other impurity |
NMT 10% NMT 5%
NMT 2.5% |
5.17% 1.12%
N.A |
Water (by Karl Fischer) | 6.0 - 10.0 % | Complies |
Sulphates | NMT 500ppm | Complies |
Arsenic (As) | NMT 3ppm | Complies |
Cadmium (Cd) | NMT 1ppm | Complies |
Mercury (Hg) | NMT 1ppm | Complies |
Lead (Pb) | NMT 10ppm | Complies |
Barium | Should comply | Complies |
Loss on drying | 6%~10% | 7.11% |
Sulphated ash | NMT 0.1% | 0.06% |
Assay(HPLC) | 99.0 %-101.0 % on dried substance | 99.3% |
Conclusion: the product conforms to BP2015 |
Sample
Available
Package
1kg/25kg per drum, or as you required.
Storage
Store the container tightly closed in a dry, cool and well-ventilated place.